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DULOXETINE VS PLACEBO FOR URINARY INCONTINENCE

DULOXETINE VS PLACEBO FOR URINARY INCONTINENCE
TAMMY RILEY
OKLAHOMA PANHANDLE STATE UNIVERSITY

STRESS INCONTINENCE
Stress urinary incontinence is the involuntary leakage of urine on effort or exertion or on sneezing, coughing, or laughing. These symptoms affect many women between the ages of 33-75 years of age. The current treatment options for stress incontinence is limited to pelvic floor muscle training, devices, behavioral interventions and surgery .
EVIDENCE BASED PRACTICE GUIDELINES
The title of the guideline is Diagnosis and treatment of overactive bladder (non-neurogenic) in adults: AUA/SUFU guidelines. The guideline was developed as a framework for diagnosis and treatment of non-neurogenic overactive bladder (OAB) and to provide direction to clinicians and patients regarding how to recognize non neurogenic overactive bladder. The direction of the study was to “conduct a valid diagnostic process and approach treatment with the goals of maximizing symptom control and patient quality of life while minimizing adverse events and patient burden” (National Guideline Clearinghouse, 2014). Another guideline objective was to serve as a guide for all types of providers who evaluate and treat OAB patients, including those in general practice as well as those who specialize in various branches of medicine.
The guideline of the evidence based practice states that the first line of treatment is behavioral therapies with combination of pharmacologic management. The second line of treatment as stated in this study is oral pharmacologic management such as oral B2-adrenoceptor agonists, transdermal oxybutynin, oral muscarinics, management of side effects and control of symptoms.
Third -line of treatment in a carefully selected patient population was intradetrusor…...

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