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Cholesterol: Genetic, Clinical and Natural Implications

In: Science

Submitted By shank91
Words 1985
Pages 8
ISSN: 0975-8585

Research Journal of Pharmaceutical, Biological and Chemical Sciences
Cholesterol: Genetic, Clinical and Natural Implications
Tanwi Priya1, Shashank Maurya2, Kishwar Hayat Khan3*
1, 2 3.

School of Biosciences and Technology, VIT University, Vellore-632014, Tamil Nadu, India. Assistant Professor (Senior), Medical Biotechnology Division, School of Biosciences and Technology, VIT University, Vellore-632014, Tamil Nadu, India.

ABSTRACT
Cholesterol is a lipid that has multiple functions. It is of great importance for cell membrane structure and function in vertebrates. Metabolites of cholesterol viz. bile salts, steroid hormones and oxysterols, fulfill important biological functions. Hypercholesterolemia is an important risk factor for cardiovascular diseases. It is caused by an imbalance between cholesterol secretions into the blood and its uptake. This article is totally based on literature survey. The authors clearly explained the types of cholesterol, their functions and actions. They explored the cholesterol at molecular level by considering genes that regulate it. A number of diseases related to cholesterol were also highlighted. Plants products which can reduce the level of cholesterol were also explored. Moreover drugs that reduce cholesterol were also focused upon and the plant products which can act as their alternative were explained. Control of cholesterol through gene expression was also discussed. The aim of writing this article is to create awareness among the readers worldwide regarding the impact of cholesterol on their health. Moreover this article will help to select food items that can reduce the level of cholesterol and thus safeguard health. Keywords: Cholesterol, Genes related to cholesterol, Diseases, Drugs, Natural foods

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Corresponding author

July-September

2013

RJPBCS

Volume 4 Issue 3

Page No.…...

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